Metabolic Strain Engineer (f/m/d)

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Job Description

As a Metabolic Strain Engineer, you will combine computational biology and wet lab work to develop and test product-oriented strain targets. You will utilise different computational biology approaches to identify novel, product-oriented targets for strain development.

  • Extend and continuously develop our computational biology capabilities further around GEMs & flux modeling, NGS datasets and structural biology - to match strain engineering needs;
  • Generate model-assisted strategies and target lists for improved yield and productivity KPIs to enhance our commercial production strain further;
  • Design, build and implement strain edits to test model-derived strategies in a wet lab environment (feeding the DBTL cycle);
  • Collect and analyse experimental data from wet lab and computational modeling; interpret, prepare and present results to drive team discussions;
  • Collaborate with the core team and external partners;
  • Help accelerate iterative DBTL cycles across teams and push towards achieving the goals regarding product composition, yield and productivity metrics. You will also build and test these targets in vivo and hands-on in the wet lab, together with the strain development team. We are hence looking for an ambitious and motivated team player with a strong passion for computational biology and the wet lab alike. You will be challenged to drive the extension and continuous improvement of applied computational tools at Planet A Foods. You will have the support of the team and leadership to grow our computational tool stack alongside your skills over time, with commitment to additional resources through our network and educational training. Together with our product-oriented A-team, you will collaboratively solve the biologic and technical challenges to make this product a reality.
  • Master's degree in Bioinformatics / Computational Biology - or in a Biology / Molecular Biology / Biotechnology / Biochemistry program with a clear personal track record of experience in computational biology - or a Bachelor’s degree with additional relevant industry experience
  • Experience with GEMs/stoichiometric flux models and NGS data analysis is highly desired
  • Experience with molecular biology techniques is a must, such as PCR, DNA cloning (ideally: Gibson, Golden Gate), as well as proficiency in microbial culture techniques (sterile working, cultivation) and basic laboratory practices
  • Excellent skillset in metabolic engineering, genetics and synthetic biology, with a passion for both computational biology applications plus wet lab strain construction work in full DBTL cycles
  • Strong analytical thinking, contextualisation and abstraction skills to navigate complex cellular networks, combined with the abilities to prioritise efficiently and communicate effectively
  • Ability to work independently and self-sufficiently as well as to contribute to a collaborative team. Plus the mindset to derive joy from a mix of both working styles.
  • Healthy, Delicious Meals: Fresh, subsidised daily lunches, along with unlimited snacks and drinks to keep you energised
  • Generous Vacation Time: 30 days of paid holiday each year to recharge and pursue your personal passions
  • Work-Life Flexibility: Flexible working hours, and a flat-hierarchy environment where collaboration and open communication thrive
  • Supporting Healthy Lifestyle: Discount to Urban Sports Club so you can stay active and fit
  • Parking Spaces: Benefit from designated parking spaces on-site
  • Team-Building Events: Strengthen connections and foster a positive team dynamic
  • Sensory Experiences: Evaluate and contribute to the flavour, colour, and aroma of both current and future recipes
  • Chocolate, Every. Single. Day: Because who wouldn't want to indulge in delicious chocolate every single day?
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